clear facts – short news 22/04/2019 – Posted in: Daily News

Earth Day

Earth Day Network works year round to solve climate change, to end plastic pollution, to protect endangered species, and to broaden, educate, and activate the environmental movement across the globe.

Each year, Earth Day—April 22—marks the anniversary of the birth of the modern environmental movement in 1970.

Earth Day 2019 Theme – Protect Our Species

 

 

Direct delivery of Protein into cells

The team of researchers at Indian Institute of Science (IISc), Bengaluru, has used a novel strategy to directly deliver proteins into mammalian cells. Researchers substituted a hydrogen atom of the protein with an iodine atom to increase in protein uptake by cells.

Proteins are big molecules and so cannot enter the cells on their own.

Source: The Hindu

 

 

MicroRNA

Analysts from Tata Institute of Fundamental Research (TIFR), Mumbai, have prevailing with regards to recognizing the mechanism that drives the feed-fast transition in the liver.

Feed-fast cycle

The feed-fast cycle is an important aspect of our body metabolism.

There are four stages to it:

  • Fed state
  • Oost-absorptive state
  • Fasting state  (During a fasting state, liver produces glucose in a process which is critical for maintaining circulating glucose levels).
  • Starvation state.

An abnormality in either of these processes can lead to diabetes, obesity or other liver diseases.

 

Fasting

Fasting can last from a few hours to days. Therefore, when going from fasting to feeding, the liver functions must switch rapidly. This entails stopping the mRNA translation of fasting-induced genes in a fed state.

 

Liver

The liver is a central organ in maintaining glucose and fat metabolism both under fed and fasted conditions.

 

MicroRNA

Both acute and chronic liver toxicity represents a major global health burden and an important cause of morbidity and lethality worldwide. Despite epochal progress in the treatment of hepatitis C virus infections, pharmacological treatment strategies for most liver diseases are still limited and new targets for prevention or treatment of liver disease are urgently needed. MicroRNAs (miRNAs) represent a new class of highly conserved small non-coding RNAs that are involved in the regulation of gene expression by targeting whole networks of so called “targets”.

 

Source: The Hindu